取扱製品 & サービス
オンターゲット株式会社では、ターゲットの探索・スクリーニング・リード化合物の最適化から、薬効薬理、薬物動態(ADME)、毒性・安全性試験など、創薬の様々なステージにマッチするサービス・試験や製品を提供・サポートしています。

Target discovery Lead optimization Pharmacology Pharmacokinetics Toxicity & Safety
Kinase, Protease, Epigenetic, HTS

SPR Technology, Biacore™, Binding assays,
Kinetics analysis, Label-free, MoA,
Real-time monitoring biomolecular interaction
   
MASS Spectrometry, Label-free,
Target-compound evaluation, Enzyme kinetic assays,
Substrate profiling, HTS
 
Epigenetics,
Histone Modification


Human tissue, serum, plasma, other speciments
Cancer, Metabolic Diseases, Autoimmune Diseases
DUB (deubiquitylase), Ubiquitin
GPCR Metabolic diseases, Adipocyte, Pancreatic Islets (GSIS assay), Skeletal Muscle Cell, Skin Cell Assays

GPCR internalization, HCS, Phenotypic Screening, CNS, Oncology, Toxicity 

Ion Channel (Nav1.1~1.9 and others) Manual and Auto patch clamp,
Transporter modulators (Zinc, Nonelectrogenic symporters and antiporters),
XRpro® (X-ray fluorescence) technology 

Ion channel, GLP / GLP-like grade, Cardiac Panel Assay, iPS-derived cardiomyocyte,
Manual patch clamp, Auto patch clamp, Fluorescence assays

Biomarkers, Proteomics, Antibody Microarray, Immunoblotting, Signal Transduction, Protein Expression, Phosphorylation, Signal Pathway

Target Engagement, Drug binding to target proteins in cells or tissues, Biomarkers, Translational study, CEllular Thermal Shift Asay - CETSA™

Oncology, PDX model, in vivo efficacy assay, in vitro cell base proliferation assay

CNS & PNS disorders, Pain, Neurology, Cognition, Inflammation, in vivo model, in virto assay, Electromyography, Histomorphometry
Human DRG, Heart, Brain, Pain, Cardiovascular, Neurodegenerative diseases

 
※掲載されている製品及び受託サービスは全て研究用です。目的を問わず人体への投与を含む、医薬品、診断用医薬品、食品、食品用検査、化粧品等の用途には使用できません。研究用以外の目的には使用しないでください。